Amsterdam: Elsevier; 2015. p. 4576. A systematic review. It improves gum health and helps reduce factors that contribute to gum recession, a leading cause of tooth sensitivity. Table 4 demonstrates a comparison between treatment groups observing better clinical efficacy in managing DH on SCASS. Dentine Hypersensitivity. All the treatment groups showed statistically significant improvement in DH with p<0.001 relative to baseline at all time points. 3. Holland GR, Narhi MN, Addy M, Gangarosa L, Orchardson R. Guidelines for the design and conduct of clinical trials on dentine hypersensitivity. Vu Pham T, Anh Nguyen T. Clinical evaluation of the desensitizing efficacy of a paste containing 8% arginine and calcium carbonate. 2017;59(4):4618. Manage cookies/Do not sell my data we use in the preference centre. Clin Cosmet Investig Dent. PubMed However, they also suggested further comparative evaluations of two dentifrices with large sample sizes as limited scientific evidence was found in previous studies [16]. This study investigated the relief from pain in DH in one minute after applying over the counter (OTC) dentifrices with Pro-Argin and strontium acetate and directly compared them with fluoro-calcium phospho-silicate (FCPS)-based dentifrices for immediate and sustained inhibition of painful stimulus provoking DH. Desensitizing toothpastes for dentin hypersensitivity: a network meta-analysis. WHAT IS Colgate SENSITIVE INSTANT Relief Repair & Prevent? Dentifrices-containing Pro-argin showed a significant reduction in DH with mean scores of (3.052.17) followed by strontium acetate (3.751.97) followed by FCPS (5.301.83) one minute after application. The outcomes are in concordance with the previous studies conducted by Layer and Hughes [26], Zang and Shaw [27], and Mason et al. In contrast, there was a significant (p<0.001) reduction of 61.1% with FCPS, 60.1% with Pro-argin, 53.4% with 8% strontium acetate, and 25% with NaF-based dentifrices relative to baseline after subsequent six weeks of application observing sustained relief from DH on SCASS. Colgate Sensitive Pro Relief Whitening Toothpaste 75ml tube (Pack of 4) Instant and Lasting Relief Clinically Proven with Active Ingredients We have a surprise for you Find out all personalised promo codes that you are eligible for. Arshad, S., Zaidi, S.J.A. YYYY Colgate-Palmolive Company. 7 Ipsos, UK Patient Experience Programme on Colgate SENSITIVE PRO-Relief, results collected after 2 weeks trial, 192 respondents, 2016. Martins C, Firmino R, Riva J, Ge L, Carrasco-Labra A, Brignardello-Petersen R, et al. Directions for Use: For instant relief, apply directly to the sensitive tooth with finger tip and massage gently for 1 minute, up to twice a day and for children 6-12 years once a week or less frequently. Colgate Sensitive Pro-Relief Instant Relief Sensitive Toothpaste - 75ml More Images Colgate Sensitive Pro-Relief Instant Relief works as a shield that blocks pathways to pain instantly. The participants with self-reported sensitivity in teeth were clinically diagnosed with DH. 1):8A-15A. OTC dentifrices were applied and massaged gently with the applicator on at least two sensitive teeth per subject at two different sites, including cementoenamel junction and exposed dentinal surface, by the doctor in the office during the first visit. West N, Newcombe RG, Hughes N, Mason S, Maggio B, Sufi F, et al. Last updated on May 11, 2021. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. [41] was performed in 2017 and reported inappropriate statistical methodologies related to the normal distribution of data and equality of variances, along with lacking information in 77.1% of the thirty-five randomised trials on DH management. Pashley D. Consensus-based recommendations for the diagnosis and management of dentin hypersensitivity. (Table 1) (Fig. Dent Health Curr Res. volume21, Articlenumber:498 (2021) There is no problem with every day and prolonged use. Work with Colgate Professional to help provide better oral care to your patients. Lasting relief with 2x daily continued brushing. Clinical efficacy of BioMin F, Colgate sensitive pro-relief and Sensodyne rapid action dentifrices in DH [Internet]. They don't. Statistical Package for the Social Sciences software v.21.0. If symptoms persist, talk to your healthcare professional. Two double-blind randomized clinical studies by Nathoo et al. p values of<0.05 were considered as statistically significant. Colgate SENSITIVE INSTANT Relief Repair & Prevent toothpaste with PRO-ARGIN Technology and Zinc provides clinically proven instant* and lasting sensitivity relief1-2 plus lasting gum protection3. Provided by the Springer Nature SharedIt content-sharing initiative. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. The widely accepted hydrodynamic theory proposes that stimuli can alter the behavior of fluid in the dentin tubules, activating intra-dental nerve fibers and causing pain. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. Can be used after the Colgate Sensitive Pro-Relief Desensitizing Paste. SA was the principal investigator and has contributed to design, data acquisition, analysis, and interpretation, and drafted the manuscript. 2017;2017:2. J Dent. Customers also search toothpaste colgate sensitive colgate enamel colgate pro relief colgate pain relief J Dent. Zinc helps strengthen gums and prevent gum recession a key cause of sensitivity1,2,3. Width 17 Height 5 Depth 3.8 Show More Payment & Refunds who examined FCPS and Pro-argin formulations in 2018. More robust trials with a large number of participants are recommended for furtherassessing the impact of DH on the oral health-related quality of life and the difference in the effectiveness of treatments. Builds a protective barrier that acts like . Gillam D, Talioti E. The Management of Dentine Hypersensitivity. * with direct application and daily brushing Benefits Exclusive Pro-Argin formula Prevents sensitivty coming back YES Somewhat No Pro-Argin technology is occlusive. J Evid Based Dent Pract. SCASS and VAS were introduced on each visit as primary and secondary outcome measures, respectively. I want to acknowledge the administrative faculty and staff assistants in the Department of Periodontology for facilitation in data collection. observed a significantly greater reduction in sensitivity from air and tactile stimuli when compared to a potassium ion toothpaste, an effect sustained at two, four and eight weeks of use. Post-hoc analysis revealed a significant reduction in DH scores in treatment arms compared to control on completing the six-week trial (p<0.05). Register now and gain access to: 8 hours ECPD Product samples Patient materials Register here * For instant relief, apply directly to the sensitive tooth with finger tip and gently massage for 1 minute. Clinically proven Instant and lasting Sensitivity relief*. Dentin hypersensitivity is characterized by a short, sharp pain arising from open dentin tubules in exposed dentin in response to external stimuli, which cannot be attributed to any other defect or disease. 90 sold. Our study included an Asian population, and most of the published literature was associated with the Caucasian population. The Colgate Sensitive Pro Relief range features toothpastes that provide relief for sensitive teeth while addressing other common oral health concerns: Colgate Sensitive Pro Relief Repair and Prevent to protect against gingival recession. These participants were randomized equally by the principal investigator into four entitled treatment arms using computer-generated random sequence numbers, and treatments were allocated randomly using sequentially numbered, opaque, sealed, and stapled envelopes (SNOSE). Shrimathi S. Effect of BiominF, NovaminR, Argin and nanohydroxy particles containing dentifrices on dentine hypersensitivity and gingivitis among 3544 years aged population of Madurai district: a randomized controlled trial (RCT). The secondary objective of the study was to compare the clinical efficacy of Pro-argin, strontium acetate, and FCPS for immediate and sustained treatment response in DH that was measured on SCASS as a primary outcome measure and VAS as secondary outcome measure at efficacy intervals of one minute, day-three, week two, four and six. compared the Pro-Argin formulation with a calcium sodium phosphosilicate toothpaste, demonstrating 88% versus 50% occlusion respectively. Identifier NCT 04249336. Buy Colgate Sensitive Pro Relief and get the best deals at the lowest prices on eBay! The current study outcomes showed significant decrease in pain scores of air-blasts and water jet stimulated DH with FCPS based dentifrices compared to Pro-argin and 8% strontium acetate after two, four, and six weeks subsequently, as depicted in Tables 4 and 5. Akber A, Ali NS, Shabbir S, Wahid U, Farooqui WA. 2010;11:32. 2013;41:S317. Last updated on May 11, 2021. https://clinicaltrials.gov/ct2/show/NCT04249336. This clinical trial was approved by the Institutional Review Board of Dow University of Health Sciences (Ref: IRB-1351/DUHS/Approval/2019/184) and was registered under the protocol ID NCT04249336 (https://clinicaltrials.gov/ct2/show/NCT04249336) on January 30, 2020, in accordance with the CONSORT statement of the updated guidelines for reporting randomised clinical trials. Product Details Characteristics and Benefits Characteristics: Unique Pro-Argin TM/MC technology based on natural process of tubule occlusion Int J Dent. Mason S, Hughes N, Sufi F, Bannon L, Maggio B, North M, et al. *Fr omedelbar lindring ska du applicera direkt p den knsliga . Free postage. All rights reserved. Dentinal tubules occluded by bioactive glass-containing toothpaste exhibit high resistance toward acidic soft drink challenge. Click & Collect. Colgate Sensitive Pro Relief Instant Relief, Plugging the channels that lead to sensitive tooth nerves to help relieve sensitivity. Helps repair teeth by forming a mineral layer that re-constructs the sensitive part of the tooth, with regular use; Seals the open nerve channels for instant relief, and helps prevent sensitivity from re-occurring; Plus the freshness you trust from Colgate The study's primary objective was to investigate pain relief in one minute after topical application of Pro-argin and strontium acetate on sensitive teeth in DH. [18] in a meta-analysis in 2020. Ingredients *Calcium carbonate *Water The next study outcome of our study wasrelated to 8% strontium acetate with clinical reduction of 37.6% on SCASS and 46% on VAS from baseline using mechanical and water jet stimuli immediately after topical application on sensitive teeth as depicted in Tables 3, 5, and 6. Mode of action studies on a new desensitizing dentifrice containing 8.0% arginine, a high cleaning calcium carbonate system and 1450 ppm fluoride. Colgate Sensitive Pro Relief was compared to a leading brand of desensitizing toothpaste containing stannous fluoride in a laboratory study, with confocal laser scanning microscopy and a novel imaging program used to qualify dentinal tubule occlusion. Trials. 2020;99(5):51422. J Oral Rehabil. * For instant relief, apply directly to the sensitive tooth with finger tip and gently massage for 1 minute. Gently removes stains and helps restore the natural whiteness of your teeth. For patients in the dental chair, it can be used to rapidly ease hypersensitivity pain, facilitate examinations and make dental procedures more comfortable. Another study by Hines et al. Madurai: Best Dental Science College; 2020. For lsting relief, apply to a gentle toothbrush making sure to brush all sensitive areas of the teeth twice daily. Saba Arshad. Plugging the channels that lead to sensitive tooth nerves to help relieve sensitivity. Colgate uses need to categorize. While FCPS in BioMin F can be the best possible treatment option for long-term management of DH in the form of OTC dentifrices. However, strontium acetate can potentially obliterate dentinal tubules by replacing the calcium ions of hydroxyapatite crystal lattice structure withstrontium ions along with its nerve depolarisation treat DH [7]. The burden of dentine hypersensitivity. Gentle whitening formula. It was measured by assaying change in SCASS scores of pains with Pro-argin and 8% strontium acetate after one minute of topical application on the sensitive teeth. Cunha-Cruz J, Wataha JC. For instant relief, apply directly to each sensitive tooth surface and massage for one minute, up to twice a day. Cite this article. The strength of this study was that participants were randomised into four treatment groups to generalise the results for the population [32]. Made by one of the best-known oral care companies in Australia, it has been clinically proven to provide both instantaneous and lasting relief from sensitivity, whilst also: Fighting cavities. Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste with Pro-Argin Technology and Zinc. 2. Participants were randomly allocated to four treatment arms and randomly assigned with OTC dentifrices having FCPS, Pro-argin, strontium acetate, and sodium fluoride (NaF) with an allocation ratio of 1:1:1:1. 1). With regular use, it reduces teeth sensitivity and helps to strengthen gums and prevent gum recession. See patient relevant information on Colgate.com. Desensitizing toothpastes depolarize the nerves to reduce pain signals to the brain, while occlusives block the dentin tubules to prevent painful stimuli affecting dentinal fluids. This toothpaste really does not help at all with symptoms of sensitive teeth. statement and Colgate Sensitive Pro-Relief Original Toothpaste This toothpaste gives you the freedom to forget about tooth sensitivity. J Clin Dent. Kp nu. . Colgate Sensitive Pro Relief Whitening for improved stain removal. Significantly greater sensitivity reduction with twice - daily brushing compared to control toothpaste with potassium ions. For best performance, keep cap closed when not in use. DH most commonly involves the facial surfaces of maxillary and mandibular permanent teeth. Comparing the efficacy in reducing dentin hypersensitivity of a new toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride to a commercial sensitive toothpaste containing 2% potassium ion: an eight-week clinical study on Canadian adults. Grading of Recommendations, Assessment, Development and Evaluations. Nathoo S, Delgado E, Zhang YP, DeVizio W, Cummins D, Mateo LR: Comparing the efficacy in providing instant relief of dentine hypersensitivity of a new toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride to a benchmark desensitizing toothpaste containing 2% potassium ion and 1450 ppm fluoride and to a control toothpaste with 1450 ppm fluoride: A three-day clinical study in New Jersey, USA. Ingredients *Calcium carbonate *Water reporting the instant relief from DH by 44.1% with Pro-argin on SCASS. Hu ML, Zheng G, Lin H, Yang M, Zhang YD, Han JM. We discuss how this innovative technology works to provide patients with rapid and long-lasting relief from dentin hypersensitivity. Based on the outcomes of previous systematic reviews and meta-analysis, the rationale of the present study was to substantiate the claim of immediate pain relief after one-minute application in DH by non-invasive surface application of OTC dentifrices containing Pro-arginin Colgate Sensitive Pro-Relief, and 8% strontium acetate in Sensodyne Rapid Action and other objective was the comparative evaluation of the clinical efficacy of three technologies, BAG-based FCPS in BioMinR F, Pro-argin, and 8% strontium acetate at efficacy intervals of day three, week two, four and six for sustained inhibition of painful stimulus provoking DH as all three are dentinal tubular occluding dentifrices.
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